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Psychopharmacology Bulletin

Psychopharmacology Bulletin PDF Book Details:
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ISBN:
Size: 71.59 MB
Format: PDF, Docs
Category : Psychopharmacology
Languages : en
Pages :
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Psychopharmacology Bulletin PDF

by , Psychopharmacology Bulletin Books available in PDF, EPUB, Mobi Format. Download Psychopharmacology Bulletin books,


Competitive Problems In The Drug Industry

Competitive problems in the drug industry PDF Book Details:
Author: United States. Congress. Senate. Select Committee on Small Business. Subcommittee on Monopoly and Anticompetitive Activities
Publisher:
ISBN:
Size: 16.56 MB
Format: PDF, Docs
Category :
Languages : en
Pages :
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Competitive Problems In The Drug Industry PDF

by United States. Congress. Senate. Select Committee on Small Business. Subcommittee on Monopoly and Anticompetitive Activities, Competitive Problems In The Drug Industry Books available in PDF, EPUB, Mobi Format. Download Competitive Problems In The Drug Industry books,


Implication Of Precorneal Factors In The Bioavailability Of Topically Applied Drugs

Implication of Precorneal Factors in the Bioavailability of Topically Applied Drugs PDF Book Details:
Author: Sukhbir Singh Chrai
Publisher:
ISBN:
Size: 69.71 MB
Format: PDF
Category :
Languages : en
Pages : 530
View: 3155

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Implication Of Precorneal Factors In The Bioavailability Of Topically Applied Drugs PDF

by Sukhbir Singh Chrai, Implication Of Precorneal Factors In The Bioavailability Of Topically Applied Drugs Books available in PDF, EPUB, Mobi Format. Download Implication Of Precorneal Factors In The Bioavailability Of Topically Applied Drugs books,


Topical Drug Bioavailability Bioequivalence And Penetration

Topical Drug Bioavailability  Bioequivalence  and Penetration PDF Book Details:
Author: Vinod P. Shah
Publisher: Springer
ISBN: 1493912895
Size: 54.62 MB
Format: PDF, ePub, Mobi
Category : Medical
Languages : en
Pages : 402
View: 6008

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Topical Drug Bioavailability Bioequivalence And Penetration PDF

by Vinod P. Shah, Topical Drug Bioavailability Bioequivalence And Penetration Books available in PDF, EPUB, Mobi Format. Download Topical Drug Bioavailability Bioequivalence And Penetration books, This authoritative volume explores advances in the techniques used to measure percutaneous penetration of drugs and chemicals to assess bioavailability and bioequivalence and discusses how they have been used in clinical and scientific investigations. Seven comprehensive sections examine topics including in vitro drug release, topical drugs products, clinical studies, and guidelines and workshop reports, among others. The book also describes how targeted transdermal drug delivery and more sophisticated mathematical modelling can aid in understanding the bioavailability of transdermal drugs. The first edition of this book was an important reference guide for researchers working to define the effectiveness and safety of drugs and chemicals that penetrated the skin. This second edition contains cutting-edge advances in the field and is a key resource to those seeking to define the bioavailability and bioequivalence of percutaneously active compounds to improve scientific and clinical investigation and regulation.


Drug Bioavailability

Drug Bioavailability PDF Book Details:
Author: Han van de Waterbeemd
Publisher: John Wiley & Sons
ISBN: 3527605150
Size: 37.57 MB
Format: PDF
Category : Science
Languages : en
Pages : 602
View: 2704

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Drug Bioavailability PDF

by Han van de Waterbeemd, Drug Bioavailability Books available in PDF, EPUB, Mobi Format. Download Drug Bioavailability books, The peroral application (swallowing) of a medicine means that the body must first resorb the active substance before it can begin to take effect. The efficacy of drug uptake depends on the one hand on the chemical characteristics of the active substance, above all on its solubility and membrane permeability. On the other hand, it is determined by the organism's ability to absorb pharmaceuticals by way of specific transport proteins or to excrete them. Since many pharmacologically active substances are poorly suited for oral intake, a decisive criterion for the efficacy of a medicine is its so-called bioavailability. Written by an international team from academia and the pharmaceutical industry, this book covers all aspects of the oral bioavailability of medicines. The focus is placed on methods for determining the parameters relevant to bioavailability. These range from modern physicochemical techniques via biological studies in vitro and in vivo right up to computer-aided predictions. The authors specifically address possibilities for optimizing bioavailability during the early screening stage for the active substance. Its clear structure and comprehensive coverage make this book equally suitable for researchers and lecturers in industry and teaching.


Dissolution Bioavailability Bioequivalence

Dissolution  Bioavailability   Bioequivalence PDF Book Details:
Author: Hamed Mahmmoud Abdou
Publisher: Mack Publishing Company
ISBN:
Size: 37.86 MB
Format: PDF, ePub, Mobi
Category : Biological availability
Languages : en
Pages : 554
View: 5025

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Dissolution Bioavailability Bioequivalence PDF

by Hamed Mahmmoud Abdou, Dissolution Bioavailability Bioequivalence Books available in PDF, EPUB, Mobi Format. Download Dissolution Bioavailability Bioequivalence books, 1. Evolution of dissolution testing 5; 2. Theory of dissolution 11; 3. Theoretical concepts for the release of a drug from dosage forms 37; 4. Effect of the physicochemical properties of the drug on dissolution rate 53; 5. Factors affecting the rate of dissolution of solid dosage forms 73; 6. Effects of storage and packaging on the dissolution of drug formulations 107; 7. Factors relating to the dissolution apparatus 115; 8. Effect of the test parameters on dissolution rate 145; 9. Dissolution of suspensions 173; 10. Dissolution of topical dosage forms (creams, gels, and ointments) 189; 11. Dissolutions of suppositories 205; 12. Dissolution characteristics of controlled-release systems 215; 13. Methods for enhancement of the drug-dissolution characteristics 265; 14. Developing a new dissolution method 285; 15. Bioavailability, definitions and historical perspective 297; 17. In vitro modeling for drug absorption 315; 18. Pharmacokinetic considerations in bioavailability studies 335; 19. Bioavailability and variations in drug blood levels 367; 20. Bioavailability and the biologic response 385; 21. Measurements of bioavailability 399; 22. General issues to be considered in conducting bioavailability studies 415; 23. Bioavailability of controlled-release dosage forms 425; 24. In vivo release and bioavailability of topical preparations 437; 25. Methods for enhancement of bioavailability 455; 26. Bioequivalence: general definitions 477; 27. Bioequivalence: case histories 481; 28. Correlation of in vitro rate of dissolution with in vivo bioavailability 491; 29. Determination of bioequivalence and its regulatory aspects 517; 30. The official bioequivalence protocols and therapeutic equivalence 533.


Bioavailability Determination Of Drugs With Michaelis Menten Elimination Kinetics

Bioavailability Determination of Drugs with Michaelis Menten Elimination Kinetics PDF Book Details:
Author: Gerald Michael Rubin
Publisher:
ISBN:
Size: 42.89 MB
Format: PDF
Category : Drugs
Languages : en
Pages : 418
View: 4467

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Bioavailability Determination Of Drugs With Michaelis Menten Elimination Kinetics PDF

by Gerald Michael Rubin, Bioavailability Determination Of Drugs With Michaelis Menten Elimination Kinetics Books available in PDF, EPUB, Mobi Format. Download Bioavailability Determination Of Drugs With Michaelis Menten Elimination Kinetics books,